Hemophilia is an X-linked recessive genetic disorder which affects approximately 400,000 people globally.Differing healthcare reimbursement systems, budgetary constraints and geographical and cultural factors make it difficult for any country to fully deliver ideal care.Although developed countries have sufficient treatment products available, they
Recent Advances in Understanding Audiovestibular Loss of a Vascular Cause
Acute audiovestibular loss is characterized by abrupt onset of prolonged (lasting days) vertigo and hearing loss.Acute ischemic stroke in the distribution of the anterior inferior cerebellar artery (AICA) is known to be the leading cause of acute audiovestibular loss.So far, eight subgroups of AICA territory infarction have been identified accordin
Lifespan differences in hematopoietic stem cells are due to imperfect repair and unstable mean-reversion.
The life-long supply of blood cells depends on the long-term function of hematopoietic stem cells (HSCs).HSCs Non-contact testers are functionally defined by their multi-potency and self-renewal capacity.Because of their self-renewal capacity, HSCs were thought to have indefinite lifespans.However, there is increasing evidence that genetically iden
Characterization of Recovered Bitumen from Coarse and Fine Reclaimed Asphalt Pavement Particles
In the current era of road construction, it is common to add a small amount of reclaimed asphalt pavement (RAP) in asphalt mixes without significantly changing properties such as stiffness and low-temperature cracking resistance.Not only can these mixes be better for the environment, but they can also improve certain properties like rutting resista
Distinct characteristics of western Pacific atmospheric rivers affecting Southeast Asia
The dynamic characteristics of atmospheric rivers (ARs) have been researched over the western North Pacific and East Asia due to their close linkage to disastrous precipitation extremes, while very little attention has been paid to the AR features from the western Pacific to Southeast Asia.This study aims to quantify the climatology, long-term tren